More than 10 million electronic bookings have now been made using Choose and Book.
This milestone comes just 12 months after the programme reached the five million bookings milestone in August 2007.
As each day passes more and more patients are benefiting from Choose and Book. Patients are now able to book their appointments electronically at a place, date and time convenient to them anywhere in the country.
Choose and Book's National Medical Director Dr Stephen Miller said: "I am very excited to have reached the 10th million electronic booking.
"It is significant because it gives a clear indication that Choose and Book is making good progress in becoming the NHS's everyday method of referral.
"My patients have responded very positively to Choose and Book and I know that their endorsement has been replicated around the country."
The role of Choose and Book in the NHS is becoming well established, with over 90 percent of GP practices having used the system over the past six weeks.
* On average around 50 percent of all outpatient referrals to see a specialist go through Choose and Book.
* All NHS Acute Trusts are now using Choose and Book, along with 91 per cent of all GP practices in England, which send over 105,000 referrals per week through the system.